Chemistry 128: Introduction to Chemical Biology
Chemistry 128: Introduction to Chemical Biology (Winter 2013, UC Irvine). Instructor: Professor Gregory Alan Weiss. Chemistry 128 provides an introduction to the basic principles of chemical biology: structures and reactivity; chemical mechanisms of enzyme catalysis; chemistry of signaling, biosynthesis, and metabolic pathways.
Lecture 17 - Terpenes and Cell Signaling, Part 1 |
Time | Lecture Chapters |
[00:06:34] | 1. Terpene |
[00:08:55] | 2. Biogenic Head-To-Tail Synthesis of Terpenes |
[00:14:41] | 3. Protein Prenylation: Localizes Protein to the Membrane |
[00:18:03] | 4. Bisphosphonate: Anti-Osteoporosis Drugs |
[00:20:27] | 5. The Rich Structural Diversity of Terpenes |
[00:34:51] | 6. Cyclization of Isoprene Oligomers |
[00:39:51] | 7. Control Over the Central Dogma |
[00:42:22] | 8. Ancient Small Molecules with Bioactivity |
[00:46:08] | 9. Arrows in Chemistry and Biology |
[00:49:11] | 10. Cell Signaling Scenarios |
[00:54:50] | 11. The 7 Signaling Pathways |
[00:56:16] | 12. Genetics to Dissect Complex Biology |
[01:01:06] | 13. Small Molecules Offer Control Over Otherwise Unavailable Phenotypes |
[01:07:48] | 14. Nuclear Hormone Receptors |
[01:18:14] | 15. In Vivo Biosynthesis of Calcitriol |
[01:19:23] | 16. Restoring Biological Function of a Mutant Vitamin D Receptor |
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