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Chemistry 128: Introduction to Chemical Biology

Chemistry 128: Introduction to Chemical Biology (Winter 2013, UC Irvine). Instructor: Professor Gregory Alan Weiss. Chemistry 128 provides an introduction to the basic principles of chemical biology: structures and reactivity; chemical mechanisms of enzyme catalysis; chemistry of signaling, biosynthesis, and metabolic pathways.

Lecture 05 - Non-Covalent Interactions, DNA

Time Lecture Chapters
[00:10:56] 1. DNA
[00:11:11] 2. The Lennard-Jones Potential
[00:14:28] 3. Rogues Gallery of Non-Covalent Interactions
[00:21:44] 4. Comparing Energetics
[00:25:06] 5. All Biology Involves Water
[00:28:36] 6. Receptor-Ligand Interactions
[00:33:01] 7. Biooligomers on Earth: Modularity
[00:34:35] 8. Form Follows Function to Biology
[00:39:51] 9. Non-Covalent Bonding Summary
[00:43:31] 10. Structure of DNA: Double Helix
[00:49:02] 11. The DNA Bases
[00:52:40] 12. The Missing 2-OH of DNA Confers Stability
[00:59:25] 13. The DNA Bases are Subject to Modification
[01:01:39] 14. Watson-Crick Base Pairs form U-Shape
[01:02:35] 15. Molecular Recognition
[01:14:13] 16. DNA Intercalation: Untwisting of DNA

Go to the Course Home or watch other lectures:

Lecture 01 - Introduction/What is Chemical Biology?
Lecture 02 - Common Tools in Chemical Biology
Lecture 03 - Reactivity and Arrow Pushing
Lecture 04 - Combinatorial Chemistry and Biology
Lecture 05 - Non-Covalent Interactions, DNA
Lecture 06 - DNA Reactivity with Small Molecules
Lecture 07 - DNA, RNA, and Cancer
Lecture 08 - RNA
Lecture 09 - RNA part 2
Lecture 10 - Proteins and Amino Acid Conformations
Lecture 11 - Proteins and Amino Acid Conformations, Part 2
Lecture 12 - Protein Functions
Lecture 13 - Protein Function and Enzymes
Lecture 14 - Glycobiology
Lecture 15 - Glycobiology and Polyketides
Lecture 16 - Glycobiology and Polyketides, Part 2
Lecture 17 - Terpenes and Cell Signaling, Part 1
Lecture 18 - Terpenes and Cell Signaling, Part 2