Chemistry 128: Introduction to Chemical Biology
Chemistry 128: Introduction to Chemical Biology (Winter 2013, UC Irvine). Instructor: Professor Gregory Alan Weiss. Chemistry 128 provides an introduction to the basic principles of chemical biology: structures and reactivity; chemical mechanisms of enzyme catalysis; chemistry of signaling, biosynthesis, and metabolic pathways.
| Lecture 12 - Protein Functions |
| Time | Lecture Chapters |
| [00:15:32] | 1. Protein Conformation |
| [00:18:28] | 2. All B-Sheet Proteins |
| [00:27:13] | 3. WD Proteins Scaffold Together Large Assemblies |
| [00:28:12] | 4. Collagen is Formed from a 3-Stranded Coil |
| [00:29:21] | 5. All a-Helical Proteins |
| [00:31:40] | 6. a/B Proteins |
| [00:33:21] | 7. Peptide Binding Domains |
| [00:39:05] | 8. Higher Order Assemblies of Proteins |
| [00:41:23] | 9. Equilibrium Constants to Describe the Strengths of Non-Covalent Interactions |
| [00:46:54] | 10. Following the Speeds of Reactions |
| [00:49:25] | 11. Rates of Non-Covalent Interactions |
| [00:50:16] | 12. Typical Rates of Binding |
| [00:53:09] | 13. Measuring Biological Potency Through Dose Responsive Curve |
| [00:56:26] | 14. Measuring Biological Response by ELISA |
| [00:59:36] | 15. Streptavidin-Biotin Offers Near Covalent Binding Affinity |
| [01:00:39] | 16. Biotinylated Reagents Used Extensively in Chemical Biology |
| [01:03:47] | 17. Enzymatic Catalysts = Catalytic Receptors |
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