Chemistry 128: Introduction to Chemical Biology
Chemistry 128: Introduction to Chemical Biology (Winter 2013, UC Irvine). Instructor: Professor Gregory Alan Weiss. Chemistry 128 provides an introduction to the basic principles of chemical biology: structures and reactivity; chemical mechanisms of enzyme catalysis; chemistry of signaling, biosynthesis, and metabolic pathways.
Lecture 09 - RNA part 2 |
Time | Lecture Chapters |
[00:21:06] | 1. RNA and Transcription Factors |
[00:26:04] | 2. Comparing Bacterial and Eukaryotic mRNA Processing |
[00:29:08] | 3. CTP Cap Methylation |
[00:30:30] | 4. Using PolyA Tails to Isolate mRNA |
[00:34:29] | 5. Eukaryotic Splicing of mRNAs |
[00:37:38] | 6. RNA Degredation Plays a Major Role |
[00:40:40] | 7. Therapeutic Anti-Sense |
[00:42:32] | 8. Modifying the Oligo Backbone |
[00:44:20] | 9. RNA Interference Used Extensively in the Lab |
[00:47:57] | 10. Where Peptide Synthesis Starts |
[00:58:26] | 11. The Genetic Code: The Language of the Codons |
[01:00:33] | 12. Decoding the DNA to Protein Sequence |
[01:01:43] | 13. How to Load the Aminoacyl tRNA |
[01:06:38] | 14. Post-Translational Modification of the N-Terminus |
[01:07:25] | 15. Inhibiting Methionine Aminopeptidase |
[01:09:59] | 16. Binding to mRNA Provides Further Regulation of Translation |
[01:10:59] | 17. Incorporating Unnatural Amino Acids |
[01:12:38] | 18. Expanding the Protein Palette |
[01:13:48] | 19. mRNA Aptamer Libraries |
[01:18:18] | 20. Puromycin Allows Covalent Linkage to the Growing Peptide During Translation |
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