Chemistry 128: Introduction to Chemical Biology
Chemistry 128: Introduction to Chemical Biology (Winter 2013, UC Irvine). Instructor: Professor Gregory Alan Weiss. Chemistry 128 provides an introduction to the basic principles of chemical biology: structures and reactivity; chemical mechanisms of enzyme catalysis; chemistry of signaling, biosynthesis, and metabolic pathways.
| Lecture 07 - DNA, RNA, and Cancer |
| Time | Lecture Chapters |
| [00:06:40] | 1. DNA Chemistry |
| [00:09:48] | 2. Cutting and Pasting DNA |
| [00:18:42] | 3. Protein Modification by PCR |
| [00:23:15] | 4. UV from Sunlight Cross-Links Thymines |
| [00:25:09] | 5. E. Coli Photolyase |
| [00:26:36] | 6. Protecting Your Cells By Sun Screen |
| [00:33:24] | 7. Cells Must Advance or Die |
| [00:34:57] | 8. DNA as a Big Nucleophile |
| [00:39:51] | 9. N-nitrosamines = Potent DNA Alkylating Agents |
| [00:45:00] | 10. Known Carcinogens |
| [00:47:44] | 11. Paradox: Cause and Cure? |
| [00:50:42] | 12. Excision Repair in Humans |
| [00:57:25] | 13. Hundreds of Mutations Required to Cause Cancer |
| [01:03:57] | 14. Sir Percival Pott |
| [01:05:19] | 15. Testicular Cancer |
| [01:06:56] | 16. P450 Substrates as Potent DNA Alkylators |
| [01:08:24] | 17. Benzopyrene: Pro-Epoxide DNA Alkylators |
| [01:10:18] | 18. Toxins from Molds Growing on Grains |
| [01:11:36] | 19. Nitrogen and Sulfur Mustards |
| [01:13:35] | 20. The Re-Evaluation of RNA's Importance |
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