Chemistry 128: Introduction to Chemical Biology
Chemistry 128: Introduction to Chemical Biology (Winter 2013, UC Irvine). Instructor: Professor Gregory Alan Weiss. Chemistry 128 provides an introduction to the basic principles of chemical biology: structures and reactivity; chemical mechanisms of enzyme catalysis; chemistry of signaling, biosynthesis, and metabolic pathways.
Lecture 13 - Protein Function and Enzymes |
Time | Lecture Chapters |
[00:00:00] | 1. Enzymes |
[00:03:20] | 2. Repeat Proteins |
[00:05:16] | 3. Equilibrium Constants |
[00:06:25] | 4. Enzymatic Catalysts = Catalytic Receptors |
[00:07:03] | 5. Michaelis Constant for Measuring Catalysis |
[00:15:30] | 6. The Perfect Enzyme |
[00:21:29] | 7. Kinases: Phosphorylation of Ser/Thr or Tyr |
[00:34:19] | 8. Why Study Single Molecules? |
[00:37:44] | 9. How to Follow Enzymatic Catalysis with Single Walled Carbon Nanotubes |
[00:41:34] | 10. Single Biomolecule Bioelectronics |
[00:44:24] | 11. Before and After Enzyme Attachment |
[00:46:29] | 12. Watching cAMP - Dependent Protein Kinase A |
[00:49:18] | 13. Further Generalization: Protein A Kinase |
[00:55:55] | 14. Lysozyme as a Model Enzyme for Glycoside Hydrolysis |
[01:08:22] | 15. Proteases Cleave Amide Bonds |
[01:12:37] | 16. Regulation of Proteases Through Pro-Enzymes |
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