CHEM 125A - Freshman Organic Chemistry I
Lecture 26 - Van't Hoff's Tetrahedral Carbon and Chirality. With his tetrahedral carbon models van't Hoff explained the mysteries of known optical isomers possessing stereogenic centers and predicted the existence of
chiral allenes, a class of molecules that would not be observed for another sixty-one years. Symmetry operations that involve inverting an odd number of coordinate axes interconvert mirror-images. Like printed words,
only a small fraction of molecules are achiral. Verbal and pictorial notation for stereochemistry are discussed.
(from oyc.yale.edu)
| Lecture 26 - Van't Hoff's Tetrahedral Carbon and Chirality |
| Time | Lecture Chapters |
| [00:00:00] | 1. Interpreting the Rotations of Light for Optically Active Compounds |
| [00:09:25] | 2. Van't Hoff's Proof of the Existence of Chiral Allenes |
| [00:19:57] | 3. Superimposition, Mirror Images and Handedness: Chirality in Alice's Looking Glass |
| [00:36:24] | 4. How Special Is Chirality? |
| [00:41:04] | 5. Conclusion: Exploring Stereochemistry |
| References |
| Lecture 26 - Van't Hoff's Tetrahedral Carbon and Chirality Instructor: Professor J. Michael McBride. Resources: Professor McBride's website resource for CHEM 125 (Fall 2008). Transcript [html]. Audio [mp3]. Download Video [mov]. |
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