Biochemistry
Biochemistry. Instructor: Prof. S. Dasgupta, Department of Chemistry, IIT Kharagpur. This course is an introductory course that will focus on basic concepts in biochemistry. The course deals with an understanding of biological macromolecules: proteins, carbohydrates, lipids, and nucleic acids. The structure and functional roles of the macromolecules will be studied in addition to fundamentals of enzyme chemistry: kinetics, mechanisms, inhibition, structure and mechanism. The course will also touch upon the basics of membrane transport and bioenergetic principles. After completion of the course, the students should be able to understand the chemical properties and three-dimensional structure of these biological macromolecules in relationship to their biological function. (from nptel.ac.in)
Lecture 16 - Nucleic Acids I |
Concepts covered in this lecture: 1) Definition of Nucleic acids, 2) Structural units of Purines and Pyrimidines, 3) Structural difference between DNA and RNA, 4) Difference between Nucleoside and Nucleotide, 5) Conformations of Sugar rings [N and S twist], 6) Torsions and bond rotation in nucleotides, 7) Formation of Nucleic Acid chains, 8) Types of Base Pairing.
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