Biochemistry
Biochemistry. Instructor: Prof. S. Dasgupta, Department of Chemistry, IIT Kharagpur. This course is an introductory course that will focus on basic concepts in biochemistry. The course deals with an understanding of biological macromolecules: proteins, carbohydrates, lipids, and nucleic acids. The structure and functional roles of the macromolecules will be studied in addition to fundamentals of enzyme chemistry: kinetics, mechanisms, inhibition, structure and mechanism. The course will also touch upon the basics of membrane transport and bioenergetic principles. After completion of the course, the students should be able to understand the chemical properties and three-dimensional structure of these biological macromolecules in relationship to their biological function. (from nptel.ac.in)
| Lecture 03 - Protein Structure I |
Concepts covered in this lecture: 1) Peptide, polypeptide and protein, 2) Hydropathy index and interaction with water, 3) Orientation of amino acid residue in solvent, 4) Torsion angle around C-N bond and C-C and Ramachandran plot, 5) Primary structure: sequence of amino acids, 6) Secondary structure: helix, beta sheet and turns, 7) Tertiary structure: packing of side chain in 3D structure, 8) Quaternary structure: association of subunits.
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