7.91J Fundamentals of Computational and Systems Biology
7.91J Fundamentals of Computational and Systems Biology (Spring 2014, MIT OCW). Instructors: Prof. Christopher Burge, Prof. David Gifford, and Prof. Ernest Fraenkel. This course is an introduction to computational biology emphasizing the fundamentals of nucleic acid and protein sequence and structural analysis; it also includes an introduction to the analysis of complex biological systems.
The MIT Initiative in Computational and Systems Biology is a campus-wide research and education program that links biology, engineering, and computer science in a multidisciplinary approach to the systematic analysis and modeling of complex biological phenomena. This course is one of a series of core subjects offered through the CSB Ph.D program, for students with an interest in interdisciplinary training and research in the area of computational and systems biology.
(from ocw.mit.edu)
| Lecture 18 - Analysis of Chromatin Structure |
This lecture begins with the epigenetic state, which regulates gene function without changing DNA. Then, how to estimate the protein occupancy of the genome via computational methods. Lastly, how to map enhancers to their regulatory targets.
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