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7.81J Systems Biology

7.81J Systems Biology (Fall 2014, MIT OCW). Instructor: Professor Jeff Gore. This course provides an introduction to cellular and population-level systems biology with an emphasis on synthetic biology, modeling of genetic networks, cell-cell interactions, and evolutionary dynamics. Cellular systems include genetic switches and oscillators, network motifs, genetic network evolution, and cellular decision-making. Population-level systems include models of pattern formation, cell-cell communication, and evolutionary systems biology. (from ocw.mit.edu)

Lecture 13 - Robustness in Development and Pattern Formation

This lecture by Prof. Jeff Gore is about the mechanisms of biological pattern formation. One mechanism discussed is diffusion.

Go to the Course Home or watch other lectures:

Lecture 01 - Introduction to the Class and Overview of Topics

Lecture 02 - Input Function, Michaelis-Menten kinetics, and Cooperativity

Lecture 03 - Autoregulation, Feedback and Bistability

Lecture 04 - Synthetic Biology and Stability Analysis in the Toggle Switch

Lecture 05 - Oscillatory Genetic Networks

Lecture 06 - Graph Properties of Transcription Networks

Lecture 07 - Feed-forward Loop Network Motif

Lecture 08 - Introduction to Stochastic Gene Expression

Lecture 09 - Causes and Consequences of Stochastic Gene Expression

Lecture 10 - Stochastic Modeling

Lecture 11 - Life at Low Reynolds Number

Lecture 12 - Robustness and Bacterial Chemotaxis

Lecture 13 - Robustness in Development and Pattern Formation

Lecture 14 - Microbial Evolution Experiments and Optimal Gene Circuit Design

Lecture 15 - Evolution in Finite Populations

Lecture 16 - Clonal Interference and the Distribution of Beneficial Mutations

Lecture 17 - Fitness Landscapes and Sequence Spaces

Lecture 18 - Evolutionary Games

Lecture 19 - Survival in Fluctuating Environments

Lecture 20 - Parasites, the Evolution of Virulence and Sex

Lecture 21 - Interspecies Interactions

Lecture 22 - Ecosystem Stability, Critical Transitions, and Biodiversity

Lecture 23 - Dynamics of Populations in Space

Lecture 24 - The Neutral Theory of Ecology