7.81J Systems Biology (Fall 2014, MIT OCW): Lecture 09 - Causes and Consequences of Stochastic Gene Expression

7.81J Systems Biology

7.81J Systems Biology (Fall 2014, MIT OCW). Instructor: Professor Jeff Gore. This course provides an introduction to cellular and population-level systems biology with an emphasis on synthetic biology, modeling of genetic networks, cell-cell interactions, and evolutionary dynamics. Cellular systems include genetic switches and oscillators, network motifs, genetic network evolution, and cellular decision-making. Population-level systems include models of pattern formation, cell-cell communication, and evolutionary systems biology. (from ocw.mit.edu)

Lecture 09 - Causes and Consequences of Stochastic Gene Expression

In this lecture, the class analyzes a simple model of gene expression, first to understand the deterministic behavior of the model, and then to look at the stochastic behavior of the model.

Go to the Course Home or watch other lectures:

Lecture 01 - Introduction to the Class and Overview of Topics

Lecture 02 - Input Function, Michaelis-Menten kinetics, and Cooperativity

Lecture 03 - Autoregulation, Feedback and Bistability

Lecture 04 - Synthetic Biology and Stability Analysis in the Toggle Switch

Lecture 05 - Oscillatory Genetic Networks

Lecture 06 - Graph Properties of Transcription Networks

Lecture 07 - Feed-forward Loop Network Motif

Lecture 08 - Introduction to Stochastic Gene Expression

Lecture 09 - Causes and Consequences of Stochastic Gene Expression

Lecture 10 - Stochastic Modeling

Lecture 11 - Life at Low Reynolds Number