BENG 100 - Frontiers of Biomedical Engineering
Lecture 07 - Cell Communication and Immunology. Professor Saltzman talks about cell communication, specifically ligand-receptor interactions that are important in maintaining homeostasis in the body. Different types of receptors and ligands, the nature of their interactions and ways to apply this into developing drugs are discussed (eg. Aldopa, Taximofen, beta-blockers). Next, Professor Saltzman talks about kinases, phosphatases, cyclic AMP and the mechanism of switching protein states. Three categories of cell communication signals are introduced: autocrine, paracrine, and endocrine. Finally, an example of cell communication using regulation/response to blood sugar level is presented. (from oyc.yale.edu)
| Lecture 07 - Cell Communication and Immunology |
| Time | Lecture Chapters |
| [00:00:00] | 1. Overview of Cell Communication |
| [00:07:41] | 2. Mechanisms of Cell Communication |
| [00:16:28] | 3. Agonists and Antagonists |
| [00:21:31] | 4. Receptors |
| [00:28:02] | 5. Protein Signal Transduction |
| [00:34:54] | 6. Autocrines, Paracrines, Endocrines |
| References |
| Lecture 7 - Cell Communication and Immunology Instructor: W. Mark Saltzman. Resources: Summary and key concepts: chapter 6 [pdf]; chapter 7 [pdf]. Transcript [html]. Audio [mp3]. Download Video [mov]. |
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