Ancient DNA and Human Evolution
Ancient DNA data have provided unprecedented insights into the recent history of our species. In particular, methodological improvements and innovations over the last ten years have advanced our ability to recover small fragments, target specific sequences, identify damage patterns, and obtain genome scale data. As a result, we have evidence for admixture among modern and archaic humans as well as greater appreciation for the complexity of population histories for modern humans around the world.
This symposium brings together researchers at the forefront of ancient DNA research and population genetics to discuss current developments and share insights about human migration and adaptation.
(from carta.anthropogeny.org)
The Phenotypic Legacy of Neandertal Interbreeding on Modern Humans. Tony Capra (Vanderbilt Univ) and his team analyzed the contribution of common Neandertal variants to over 1000 electronic health record (EHR)-derived phenotypes in ~28,000 adults of European ancestry. Their results establish that archaic admixture influences disease risk in modern humans, provide hypotheses about the effects of hundreds of Neandertal haplotypes, and demonstrate the utility of HER data in evolutionary analyses.
| 7. The Phenotypic Legacy of Neandertal Interbreeding on Modern Humans |
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