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Chemistry 203: Organic Spectroscopy

Chemistry 203: Organic Spectroscopy (Fall 2011, UC Irvine). These videos are part of a 28-lecture graduate-level course titled "Organic Spectroscopy" taught at UC Irvine by Professor James Nowick. The course covers infrared (IR) spectroscopy, mass spectrometry, and nuclear magnetic resonance (NMR) spectroscopy, the latter of which is the main focus. Topics covered in the NMR spectroscopy part of the course include chemical shifts, spin-spin coupling, dynamic effects in NMR spectroscopy, and 2D NMR spectroscopy (COSY, HMQC, HMBC, TOCSY, NOESY, ROESY).

Lecture 16 - The Importance of 13C Chemical Shifts in Structure and ...

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Lecture 01 - Infrared Spectroscopy: Introduction, Theory, Instrumentation, and Sample Preparation

Lecture 02 - Infrared Spectroscopy: C,H,O-Containing Functional Groups

Discussion 1 - Molecular Modeling with PyMOL

Lecture 03 - Effect of Ring Size Conjugation Electron-Withdrawing Groups

Lecture 04 - Mass Spectrometry: Theory, Instrumentation, and Techniques

Lecture 05 - Isotopic Masses, Isotopic Abundances, and High-Resolution Mass Spectrometry

Lecture 05A - Isotopic Masses, Isotopic Abundances, and High-Resolution Mass Spectrometry

Lecture 06 - Fragmentation in EIMS: Alkanes, Alkenes, Heteroatom Compounds, Carbonyl Compounds

Lecture 06A - Fragmentation in EIMS: Alkanes, Alkenes, Heteroatom Compounds, Carbonyl Compounds

Lecture 07 - Introduction to NMR Spectroscopy: Concepts and Theory, Part 1

Lecture 08 - Introduction to NMR Spectroscopy: Concepts and Theory, Part 2

Lecture 09 - Chemical Shift. 1H NMR Chemical Shifts

Lecture 10 - 13C NMR Chemical Shifts. Chemical Equivalence and Spin-Spin Coupling

Lecture 11 - Magnetic Equivalence, Spin Systems, and Pople Notation

Lecture 12 - Coupling Analysis in First-Order and Near-First-Order Systems

Lecture 13 - Coupling Analysis in First-Order and Near-First-Order Systems (cont.)

Lecture 14 - Spin-Spin Coupling in Stereochemistry and Structure Determination

Lecture 15 - Coupling Involving Other Nuclei

Lecture 16 - The Importance of 13C Chemical Shifts in Structure and Stereochemistry Determination

Lecture 17 - Introduction to 2D NMR Spectroscopy

Lecture 18 - Dynamic Effects in NMR Spectroscopy

Lecture 19 - The Nuclear Overhauser Effect in Stereochemistry and Structure Determination

Lecture 20 - Understanding Complex Pulse Sequences

Lecture 21 - Using HMBC to Help Solve Structures: "Putting the Pieces Together"

Lecture 22 - Aspects of COSY, HMQC, HMBC, and Related Experiments

Lecture 23 - Using TOCSY to Elucidate Spin Systems. ROESY

Lecture 24 - Using Organic Spectroscopy to Solve Complex Structures

Lecture 25 - INADEQUATE. Some Thoughts on Homework Set 9

Lecture 26 - Using Organic Spectroscopy to Solve Complex Structures, Part 2

Lecture 27 - Using HMQC-TOCSY or HSQC-TOCSY to Deal with Overlap

Lecture 28 - Some Other Useful NMR Techniques