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Human Molecular Genetics

Human Molecular Genetics. Instructor: Prof. S. Ganesh, Department of Biological Scientists and Bioengineering, IIT Kanpur. This is an introductory course designed primarily for students interested in biomedical research, genetic counseling, medicine, and clinical genetics. This course introduces the rapid advancements in our understanding the role of human genome in health and disease. We would introduce key concepts of inheritance of human traits, pedigree analysis, and chromosome organization. Molecular biology tools used for understanding the genome, gene structure and gene mutations, gene mapping and gene cloning strategies will also be covered. Objectives and outcome of human genome project and the HapMap project will also be discussed at the end. (from nptel.ac.in)

Lecture 02 - Introduction to Exceptions to Central Dogma of Molecular Biology

This lecture will introduce exceptions to central dogma of molecular biology, and will provide an overview on how changes in the DNA could influence the function of the protein and the organism.


Go to the Course Home or watch other lectures:

Lecture 01 - An Overview on the Central Dogma of Molecular Biology
Lecture 02 - Introduction to Exceptions to Central Dogma of Molecular Biology
Lecture 03 - An Overview of the Molecular Basis of Mutations
Lecture 04 - Chromosome Structure and Function
Lecture 05 - Pedigree Analysis
Lecture 06 - Complications in Mendelian Pedigree Patterns
Lecture 07 - DNA Cloning and Hybridization Techniques
Lecture 08 - DNA Cloning and Hybridization Techniques (cont.)
Lecture 09 - Practice Session: Problems related to Pedigree Analysis
Lecture 10 - Practice Session: Fragment Length Polymorphism and its Applications
Lecture 11 - Mutations and Instability of Human DNA
Lecture 12 - Mutations and Instability of Human DNA (cont.)
Lecture 13 - Animal Models for Human Diseases
Lecture 14 - Positional Cloning of Genes for Monogenic Disorders
Lecture 15 - Human Genome Project and the HapMap Project