Biomaterials for Bone Tissue Engineering Applications
Biomaterials for Bone Tissue Engineering Applications. Instructor: Prof. Bikramjit Basu, Materials Research Centre, IISc Bangalore. Biomaterials, recognized as a new class of materials in the Materials Science community, are being developed in last few decades for human health care. The design and development of biomaterials requires the integration of the concepts and expertise from two widely different disciplines, i.e. Materials Science & Engineering and Biological Science. This course will consist of several lectures on the basics of the cell biology and biomaterials science, followed by some case studies, illustrating various aspects of biomaterials development for orthopedic applications. The layout of this lecture series in terms of the succession of various concepts will primarily facilitate easier understanding for students and this important area of societal relevance in terms of human healthcare.
(from nptel.ac.in)
| Introduction to Biomaterials and Biocompatibility |
| Lecture 01 - Introduction |
| Lecture 02 - Biomaterials |
| Lecture 03 - Biocompatibility |
| Lecture 04 - Biocompatibility and Host Response |
| Defining Tissue Engineering Scaffolds and Implants |
| Lecture 05 - Biological Cells |
| Lecture 06 - Cytoskeletal Structure, Cell Adaptation Processes, Protein |
| Lecture 07 - Bone Structure |
| Lecture 08 - Bone Properties |
| Lecture 09 - Fracture Toughness, Key Concepts of Biomaterials |
| Lecture 10 - Key Concepts of Biomaterials (cont.) |
| Structure and Properties of Proteins and Cells |
| Lecture 11 - Proteins |
| Lecture 12 - Cell Structure, Cell Signaling Process |
| Lecture 13 - Bacteria: Structure and Properties |
| Lecture 14 - Antibacterial Assays |
| Stem Cells and Cell Fate Processes |
| Lecture 15 - Cell Fate Processes; Cell Migration; Cell Division |
| Lecture 16 - Cell Differentiation, Polymerase Chain Reaction, Cell Death |
| Lecture 17 - Stem Cells |
| Lecture 18 - Stem Cell Differentiation |
| Cell-Material Interaction (In Vitro and In Vivo) and Clinical Trials |
| Lecture 19 - In Vivo Biocompatibility Assessment |
| Lecture 20 - In Vivo Biocompatibility (cont.) |
| Lecture 21 - Cell-Material Interaction |
| Lecture 22 - Cell Signaling |
| Lecture 23 - In Vitro Testing |
| Lecture 24 - Osteocalcin Assay, Immunofluorescence Assays |
| Lecture 25 - Biocompatibility Assay |
| Lecture 26 - Clinical Trials |
| Lecture 27 - Clinical Trials (cont.) |
| Manufacturing of Biomaterials (Metals, Ceramics and Polymers) |
| Lecture 28 - Basic Manufacturing Processes of Metallic Biomaterials |
| Lecture 29 - Fundamentals of the Ceramics Processing |
| Lecture 30 - Fundamentals of Polymers and Polymers Processing |
| Lecture 31 - Additive Manufacturing of Porous Scaffolds for Bone Tissue Engineering Applications |
| HA-based Composites |
| Lecture 32 - Osteoblast Cell Fate and High Toughness of Hydroxyapatite-Titanium Composites |
| Lecture 33 - Hydroxyapatite-based Multifunctional Composites for Bone Tissue Engineering Applications |
| Lecture 34 - Multifunctional HA-CaTiO3 Biocomposite for Bone Replacement Applications |
| Lecture 35 - Hydroxyapatite-Zinc Oxide Composites, Cell Fate and Antimicrobial |
| Lecture 36 - Synthesis, Antimicrobial and Cell Viability of Silver Doped Hydroxyapatites |
| Glass Ceramics for Orthopedic and Dental Applications, Acetabular Socket and Femoral Head |
| Lecture 37 - Processing and Properties of Dental Glass Ceramics |
| Lecture 38 - Biocompatibility of Sr-based Glass Ceramics |
| Lecture 39 - HDPE-HA-Alumina based Acetabular Socket for Total Hip Replacement Surgery |
| Lecture 40 - Near-net Shaped Ceramic Femoral Ball Head |
| References |
Biomaterials for Bone Tissue Engineering Applications
Instructor: Prof. Bikramjit Basu, Materials Research Centre, IISc Bangalore. Biomaterials, recognized as a new class of materials in the Materials Science community, are being developed in last few decades for human health care.
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