HST.512 Genomic Medicine (Spring 2004, MIT OCW) | Health and Medicine

HST.512 - Genomic Medicine

HST.512 Genomic Medicine (Spring 2004, MIT OCW). Instructor: Professor Isaac Kohane. This course reviews the key genomic technologies and computational approaches that are driving advances in prognostics, diagnostics, and treatment. Throughout the semester, emphasis will return to issues surrounding the context of genomics in medicine including: what does a physician need to know? what sorts of questions will s/he likely encounter from patients? how should s/he respond? Lecturers will guide the student through real world patient-doctor interactions. Outcome considerations and socioeconomic implications of personalized medicine are also discussed. (from ocw.mit.edu)

Lecture 01 - Genomic Introduction

Lecture 02 - Introduction to Biology and Genomic Measurement

Lecture 03 - Measurement Techniques

Lecture 04 - Microarray: Massively Parallel Measurement

Lecture 05 - Limits of Technologies

Lecture 06 - Information Science at the Center of Genomic Medicine

Lecture 07 - Informational Resources

Lecture 08 - Complex Traits: What to Believe

Lecture 09 - Machine-Learning Approach

Lecture 10 - Association with Markers

Lecture 11 - The Importance of Data Representation

Lecture 12 - Pharmacogenomics

Lecture 13 - Case Hx: Complex Traits

Lecture 14

Lecture 15 - Microarray Disease Classification

Lecture 16 - Microarray Disease Classification II

Lecture 17 - Direct Prediction of Outcome/ Mortality

Lecture 18 - Case Hx: Cancer Diagnostics

Lecture 19 - Modeling and Reverse Engineering

Lecture 20 - Practical Genomic Medicine

References

HST.512 Genomic Medicine, Spring 2004
Instructor: Professor Isaac Kohane. Selected Lecture Notes. Assignments. This course reviews the key genomic technologies and computational approaches.