Chemistry 201: Organic Reaction Mechanisms I
Chemistry 201: Organic Reaction Mechanisms I (Fall 2012, UC Irvine). Instructor: Professor David Van Vranken.
Why is it that organic chemists can't seem to agree on how to draw plausible arrow-pushing mechanisms?
In this course we connect frontier molecular orbital theory and mechanistic arrow-pushing in elementary reaction steps.
By equating the interactions between filled orbitals and un-filled orbitals with curved arrows, and distinguishing them
from Coulombic interactions, we collimate seemingly endless depictions into a plausible few.
| Lecture 01 - Arrow Pushing, Part 1 |
| Lecture 01 - Arrow Pushing, Part 2 |
| Lecture 02 - Molecular Orbital Theory |
| Lecture 02 - Molecular Orbital Theory (cont.), Energy |
| Lecture 03 - Energy |
| Lecture 04 - Selectivity |
| Lecture 05 - Carbocations |
| Lecture 06 - Carbocation Stabilization by Vicinal Sigma Bonds |
| Lecture 07 - Non-classical Carbocations (cont.), Neighboring Groups |
| Lecture 08 - Neighboring Groups in Ionization Reactions and Solvation |
| Lecture 09 - Addition to Sigma Star: Proton Transfer |
| Lecture 09 - Addition to Sigma Star: Proton Transfer (cont.), S_N2 Reactions |
| Lecture 10 - Addition to Sigma Star: S_N2 Reactions (cont.), Migratory Displacements |
| Lecture 11 - Eliminations |
| Lecture 11 - Eliminations (cont.), Addition to Pi Star |
| Lecture 12 - Addition to Pi Star (cont.) |
| Lecture 12 - Addition to Pi Star (cont.) |
| Lecture 13 - Anions |
| Lecture 13 - Anions (cont.), Alkali Organometallics |
| Lecture 14 - Alkali Organometallics (cont.) |
| Lecture 14 - Alkali Organometallics (cont.), Electrophilic Addition to C=C |
| Lecture 15 - Electrophilic Addition to C=C (cont.) |
| Lecture 15 - Electrophilic Addition to C=C (cont.) & Lecture 16. C-C Bonds |
| Lecture 17 - Enols, Enamines and Enolates |
| Lecture 19 - Sulfur Chemistry |
| Lecture 20 - Phosphorus Chemistry |